SMB
For the separation of larger quantities (from 5-10kg) SMB can be an alternative to classical batch chromatography. SMB is a continuous chromatography method with several columns connected in series.Up to 90% less solvent can be used, because it is circulated. Lower product losses and higher productivity lead to better economic efficiency, but also allow larger production volumes.
If you want to separate substances of this size, the SMB can be an alternative to conventional batch chromatography.